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NIDA Notes Articles: People with Drug Use Disorders

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Methamphetamine Turns Helper Cells Into Destroyers

November 2009
Describes research providing evidence that chronic methamphetamine abuse is associated with increased microglial cell activity in the brain leading to neurodegeneration.

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DESPR Identifies Drug Abuse Trends and Seeks Solutions

November 2009
Discusses the work of NIDA’s Division of Epidemiology, Services and Prevention Research, organized to track drug use and provide empirically based information for researchers and service providers.

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Patch Delivers Buprenorphine for Heroin Detox

November 2009
Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.

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Most People Entering Drug Treatment Have Additional Mental Health Problems

November 2009
Highlights data on the prevalence of people entering substance abuse treatment programs who also reported having at least one co-occurring mental health problem.

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Smokers Who Quit May Have Genetic Advantage

November 2009
Describes research providing evidence that genes may influence how successful a person is in quitting smoking and which cessation technique may work best for them.

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Computer-Based Interventions Promote Drug Abstinence

November 2009
Discusses the work of researchers who have begun to harness the potential of computers to reinforce and expand upon the well-established benefits of recovery therapy delivered by a counselor.

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Nicotine Boosts Mood, Brain Dopamine Levels

November 2009
Highlights findings from a study showing that nicotine triggers a surge in levels of the neurotransmitter dopamine in the brain's main reward area for cigarette smokers.

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Naltrexone via Skin Patch Proves Effectiveness of New Technology

November 2009
Reports on a new device that creates tiny painless punctures in the skin to allow medication to flow evenly from a skin patch into dermal capillaries and the bloodstream.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

October 2009
Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Suiting Treatment to the Nature of the Disease

October 2009

Highlights NIDA-sponsored research underway to understand and respond to substance abusers’ needs at all points of care, from the initial presentation for treatment through recovery.

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