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NIDA Notes Articles

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Animal Study Suggests Marijuana May Affect Future Offspring’s Susceptibility to Heroin

February 2015

Can marijuana use put offspring at heightened risk for opiate addiction, even if the use stops before the offspring are conceived? Results from a recent NIDA-funded study are consistent with other studies suggesting that a parent’s history of drug use, even preconception, may affect a child’s brain function and behavior.

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Waletzky Memorial Award Winners’ Lectures at NIDA Illuminate Cocaine’s Many Effects on Brain Structure, Circuitry

January 2015

Dr. Paul E. M. Phillips spoke on “Phasic Dopamine Transmission During Substance Abuse,” describing investigations that he has led into the role of brief, seconds-long bursts of dopamine signaling in addictive processes. Dr. Rita Z. Goldstein spoke on “Targeting the Brain, Cognition, and Motivation for Intervention in Addiction.”

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Narrative of Discovery: In Search of a Medication To Treat Methamphetamine Addiction

January 2015

This is the first in a series of NIDA Notes articles that will follow a team of researchers seeking a medication for methamphetamine addiction. This installment describes the early promise of the compound lobeline and the new directions the team discovered in studying it.

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Communities That Care System Helps Prevent Problem Behaviors in Youth Through 12th Grade

December 2014

Extending the prevention interventions to target risk factors through the high school years could strengthen effects on substance use and delinquent behaviors on the cusp of adulthood.

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Varenicline Helps People With Mental Illness Maintain Abstinence From Smoking

November 2014

The finding from an 18-month-long clinical trial strengthens hope that pharmacotherapy can break nicotine’s especially tenacious hold on people with serious mental illness such as bipolar disorder or schizophrenia.

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Study Assesses Functional Deficits Due to HIV and Methamphetamine Use

November 2014

Methamphetamine use and HIV infection raise the risk for functional dependence, or the need for assistance with everyday tasks. People who use methamphetamine and are HIV positive showed the highest levels of functional dependence in most domains of daily life.

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NIDA To Provide Travel Awards to Junior Investigators Conducting Research Focused on Women and Sex/Gender Differences in Drug Abuse

November 2014

NIDA plans to provide $750 travel awards to 27 junior investigators to present their research on women or sex/gender differences in any area of drug abuse at the annual meeting of the College on Problems of Drug Dependence in Phoenix, Arizona, June 13–18, 2015. Deadline to apply is December 5, 2014.

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Animation: The Rise and Fall of the Cocaine High

November 2014

This animation shows the rapid passage of cocaine through the brain. It demonstrates that the intensity of the cocaine “high” parallels the trajectory of cocaine levels in the brain.

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Smoking Cessation Does Not Interfere With Recovery From Substance Use

October 2014

Despite common concerns that encouraging patients to quit smoking might endanger their success in treatment of substance use and mood or anxiety disorders, smoking cessation appears unlikely to hinder and may even help recovery.

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Dr. Kevin M. Gray Q & A: A Potential Medication for Marijuana Dependence

October 2014

Dr. Kevin M. Gray discusses why it’s the perfect time for discovering new evidence-based treatments for marijuana dependence. In an accompanying podcast, he discusses a clinical trial that examines NAC’s potential as a treatment for marijuana dependence among adults.

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