NIDA Notes Articles: Heroin

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Program Helps Troubled Boys Reduce Substance Abuse

December 2011
Chronically delinquent boys in Multidimensional Treatment Foster Care reduced their substance abuse more than boys assigned to Community Group Care.

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Prison Use of Medications for Opioid Addiction Remains Low

July 2011
Describes results from a nationwide survey among correctional facilities on the use of opioid replacement therapy for people who are addicted to heroin.

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Detoxification Services and Pharmacotherapies Lacking in Nation's Jails and Prisons

December 2010
Reports findings from a survey that revealed that although substance abuse is prevalent in jails and prisons, many correctional facilities do not offer detoxification services or therapies to aid in maintaining abstinence.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Anticipation of Methadone Enhances Brain Reactivity to Heroin Cues

December 2009
Describes findings of a study revealing that images of heroin preparation and injection can incite craving and excite brain areas associated with reward-seeking even in methadone-maintained patients.

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Naltrexone via Skin Patch Proves Effectiveness of New Technology

November 2009
Reports on a new device that creates tiny painless punctures in the skin to allow medication to flow evenly from a skin patch into dermal capillaries and the bloodstream.

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Patch Delivers Buprenorphine for Heroin Detox

November 2009
Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.

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Lofexidine May Enhance Naltrexone Efficacy

December 2008
Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Basic Science Discoveries Yield Novel Approaches to Analgesia

September 2008
Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.

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Reduced Longevity Among Male Heroin Abusers, 1962-1997

June 2008
Reviews the changing lifespan of heroin abusers as compared with that of the general U.S. population based on 1962-1997 data.