NIDA Notes Articles: Genetics

PhenX Toolkit Provides Standard Measures for Research

July 2012
NIDA researchers working with human subjects now have a new resource at their fingertips: the PhenX Toolkit’s new Substance Abuse and Addiction (SAA) Collection. The Toolkit is designed to provide standardized measures, vetted and approved by the field, to help researchers compare and combine data from multiple studies.

In Animals, Receptor Puts Brakes on Nicotine Consumption

March 2012

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

Gene Influences Impact of Maternal Smoking on Children's Behavioral Problems

July 2011
Describes research showing that the combination of prenatal smoking exposure and specific genes increases children’s and adolescent’s risk for behavior problems.

Three Scientists Join Advisory Council

December 2010
Announces three new NIDA National Advisory Council on Drug Abuse members and describes their drug abuse and addiction research experience.