Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.
Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.
Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.
Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.
Describes research findings demonstrating that the immune system participates in the shaping of brain circuits during a child's development, a finding that may shed light on the origins of neurodegenerative diseases.
Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.
Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.
Announces the three winners of the NIDA and Scholastic Corporation 2008 Addiction Science Awards honoring high school students’ award-winning addiction-related projects.
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.