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NIDA Notes Articles

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

October 2007

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Among Young Attendees at STD Clinics, Substance Abusers Report More Risky Sexual Behavior

October 2007

Highlights data on the risky sexual behaviors of patients at a sexually transmitted disease clinic who had a substance abuse disorder as compared to those without a substance abuse disorder.

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Adolescent Inhalant Use Is Stable Overall, but Rising Among Girls

October 2007

Reports patterns and trends in inhalant use among adolescents based on an analysis of data from a 2002-2005 national survey on drug use and health.

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Study Links Anabolic Steroids to Brain Changes in Adolescent Female Mice

October 2007
Reports on an animal study finding that links anabolic steroids to brain changes in adolescent female mice, changes that can potentially lead to steroid abuse.

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Impacts of Drugs on Neurotransmission

October 2007

Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

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Antipsychotic Drug Prevents Morphine Tolerance in Mice

April 2007
Summarizes animal studies indicating that an antipsychotic drug, trifluoperazine, prevents morphine tolerance in mice.

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Depot Naltrexone Appears Safe and Effective for Heroin Addiction

April 2007
Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

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Uneven Regional Brain Development Contributes to Adolescent Risk-Taking

April 2007

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

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