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NIDA Notes Articles: Genetics
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Stress Receptor Mediates Lifelong Consequences of Early Trauma

November 2012

NIDA-supported research suggests that glucocorticoid receptor levels during early brain development affect the hard wiring of neural circuits that shape an individual’s basic emotional makeup. In mice, overexpression of the glucocorticoid gene in the first weeks after birth increased anxiety and response to cocaine in adulthood. These findings may help researchers understand the genetic background and the developmental trajectory of addiction.
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Studies Link Family of Genes to Nicotine Addiction

December 2009

Reports study results suggesting that genes for several acetylcholine receptor proteins influence early smoking responses and the likelihood of nicotine dependence.
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Three Scientists Join Advisory Council

December 2010
Announces three new NIDA National Advisory Council on Drug Abuse members and describes their drug abuse and addiction research experience.

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Workgroup Directs Search for Genes That Influence Addiction

April 2010
Highlights NIDA’s research portfolio to identify the genes and genetic processes responsible for a person’s vulnerability to drug abuse.

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