November 2009 Discusses the work of NIDA’s Division of Epidemiology, Services and Prevention Research, organized to track drug use and provide empirically based information for researchers and service providers.
Describes research exploring differences and similarities in the genetic profiles of African-Americans and European-Americans who are heavy smokers.
Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.
Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.
Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.
Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.
Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.
Reports on the research underway to identify gene variations associated with nicotine addiction and the interaction of genetic makeup, experiences, and surroundings to addiction.