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NIDA Notes Articles: Comorbidity
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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

October 2009

Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.
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Low Dopamine Receptor Availability May Promote Cocaine Addiction

April 2009

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
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Research Addresses Needs of Criminal Justice Staff and Offenders

April 2009

Highlights a project in which nine research centers collaborate with criminal justice partners to test science-based tools for integrating drug abuse treatment in prisons and probation and parole programs.
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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009

Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.
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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women

December 2008

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.
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New Therapy Reduces Drug Abuse Among Patients With Severe Mental Illness

June 2008

Describes a new intervention that enhances recovery prospects for substance abusers whose mental illness complicates the path toward recovery.
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Researchers Report on Progress of NIDA's Southern Africa Initiative

March 2008
Presents an update on NIDA’s Southern African Initiative, a program that aims to build research capacity and infrastructure in the area of addiction, particularly drug-related HIV transmission.
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Gene Experiment Confirms a Suspected Cocaine Action

October 2007
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.
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Standard Treatments Help Depressed Smokers Quit

April 2007
Describes a study comparing Staged Care Intervention, a combination treatment for smoking cessation, among smokers in outpatient treatment for depression and a control group.

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Report Calls for Sweeping Changes in Health Care for Mental and Substance Abuse Problems

February 2007
Reviews a report from the National Academy of Sciences’ Institute of Medicine that discusses ways to improve the quality of health care among people with mental health and substance abuse disorders.

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