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NIDA Notes Articles: Clinical Trials Network

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Addiction and Co-Occurring Mental Disorders

February 2007

Presents an overview of the research underway to investigate medication and behavioral therapies for co-occurring disorders.

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Alleviation of Posttraumatic Stress Disorder May Improve Addiction Treatment

April 2012

Women with posttraumatic stress disorder (PTSD) who abused drugs responded better to substance abuse treatment after their PTSD symptoms improved, according to a recent study, which also found that reductions in substance abuse did not ease PTSD severity

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Dr. Kathleen T. Brady Recognized

October 2010
Recognizes the 2010 Distinguished University Professor awardee, Dr. Kathleen T. Brady, who studies co-occurring substance abuse and mental health disorders and their treatment.

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Dr. Kevin M. Gray Q & A: A Potential Medication for Marijuana Dependence

October 2014

Dr. Kevin M. Gray discusses why it’s the perfect time for discovering new evidence-based treatments for marijuana dependence. In an accompanying podcast, he discusses a clinical trial that examines NAC’s potential as a treatment for marijuana dependence among adults.

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Dr. Phil Skolnick Now Leads NIDA's Medications Development Efforts

April 2010
Announces the appointment of Dr. Phil Skolnick as NIDA’s director of the Division of Pharmacotherapies and Medical Consequences of Drug Abuse.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance

April 2007

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Intensive Interventions Reduce Risky Sexual Behaviors

July 2011
Discusses research that compares multiple sessions of motivational and behavioral training with that of a single intervention among male and female substance abusers to reduce high-risk sexual behaviors.

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Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

October 2006
Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.

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Medications That Treat Opioid Addiction Do Not Impair Liver Health

December 2013

A trial of buprenorphine/naloxone (Bup/Nx) showed no evidence that the medicine was associated with liver damage. The drug gave results similar to those of methadone. The study data indicate that although most patients can be treated safely with either methadone or Bup/Nx without major concern for liver injury, clinicians are advised to continue to monitor the liver health of their patients who are on methadone or Bup/Nx therapy.

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NIDA Announces Avant-Garde Medication Development Awards

March 2012
Dr. Thomas Kosten of Baylor College of Medicine and Dr. Peter Burkhard of the University of Connecticut are the recipients of NIDA’s 2011 Avant-Garde Awards for Innovative Medication Development Research. Dr. Kosten is developing a vaccine against methamphetamine abuse and Dr. Burkhard is developing a vaccine to counter nicotine addiction.

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