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NIDA Notes Articles: Addiction Science

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

October 2007

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Neuropeptide Promotes Drug-Seeking and Craving in Rats

October 2007
Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

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NIDA Investigator Receives 2006 Waletzky Memorial Award

April 2007
Announces the recipient of a 2006 award for innovation in research on drug addiction and alcoholism, Dr. Yavin Shaham, and describes his research which focused on the stress-induced drug use relapse.

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Scientists Pinpoint Brain's Sweet Tooth

April 2007
Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.

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Brain Changes Accompany Cocaine Withdrawal

February 2007
Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

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Cocaine Craving Activates Brain Reward Structures; Cocaine "High" Dampens Them

February 2007
Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.

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Nicotine Alters the Developing Rat Brain

February 2007
Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

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NIDA's National Advisory Council Welcomes New Members

October 2006
Introduces four new members to NIDA’s National Advisory Council on Drug Abuse, including Drs. Warren K. Bickel, Ellie E. Schoenbaum, and Marina E. Wolf, and Ms. Janet Wood.

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