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NIDA Notes Articles: Addiction Science

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Chromosome 17 Harbors Opioid Dependence Genes

March 2008

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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Cocaine Can Mobilize Stored Dopamine

March 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Epigenetics: The Promise of a New Science

March 2008

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Researchers Develop a New Tracer for Cannabinoid Receptor

March 2008
Describes a new chemical tracer that binds specifically to cannabinoid receptors making it potentially useful in future research to clarify the relationship between the receptors and drug abuse.

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Not All Mesolimbic Dopamine Neurons Are Alike

March 2008

Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.

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NIDA Will Contribute to Obesity Research

October 2007

Describes an NIH-wide obesity task force and research plan and explores some of the links between addiction and compulsive eating.

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NIDA's Newest Division Mines Clinical Applications From Basic Research

October 2007

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Tracing NET

October 2007
Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.

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Impacts of Drugs on Neurotransmission

October 2007

Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

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