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NIDA Notes Articles: Addiction Science

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Long-Term Cocaine Abuse Linked With Impaired Heart Function

March 2008
Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.

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Alcohol Abuse Makes Prescription Drug Abuse More Likely

March 2008
Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

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Cocaine Can Mobilize Stored Dopamine

March 2008
Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Epigenetics: The Promise of a New Science

March 2008

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Researchers Develop a New Tracer for Cannabinoid Receptor

March 2008
Describes a new chemical tracer that binds specifically to cannabinoid receptors making it potentially useful in future research to clarify the relationship between the receptors and drug abuse.

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Neuropeptide Promotes Drug-Seeking and Craving in Rats

October 2007
Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

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NIDA Will Contribute to Obesity Research

October 2007

Describes an NIH-wide obesity task force and research plan and explores some of the links between addiction and compulsive eating.

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NIDA's Newest Division Mines Clinical Applications From Basic Research

October 2007
Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Tracing NET

October 2007
Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.

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