Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.
Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.
Announces the three winners of the NIDA and Scholastic Corporation 2008 Addiction Science Awards honoring high school students’ award-winning addiction-related projects.
Describes research findings demonstrating that the immune system participates in the shaping of brain circuits during a child's development, a finding that may shed light on the origins of neurodegenerative diseases.
Describes new tools under development, including one to visualize cells deep in the brain and another one that remotely activates brain cells.
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.
Describes a booklet that explains what scientists know about how drug addiction changes the brain and affects behavior and clears up misconceptions about drug addiction.