Describes NIDA’s drug abuse and addiction research priorities for the use of the American Recovery and Reinvestment Act of 2009 funds.
Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.
Presents highlights of a symposium sponsored by NIDA in October 2008 to discuss adolescent brain and cognitive development and consider the impact of drug abuse on young people.
Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.
Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.