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NIDA Notes Articles: Addiction Science

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Adolescent Rats Self-Administer More Nicotine Than Adults

April 2009

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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NIDA Initiates Pediatrics Symposium on Adolescent Health

April 2009

Presents highlights of a symposium sponsored by NIDA in October 2008 to discuss adolescent brain and cognitive development and consider the impact of drug abuse on young people.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

April 2009

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.

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Methamphetamine Abusers Show Increased Distractibility

April 2009

Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.

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Damage to Brain Area May Immediately Halt Cigarette Addiction

April 2009

Describes a study among people who had sustained brain injuries to investigate whether certain damaged areas of the brain are associated with the ability to quit smoking.

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New Tracer for Nicotinic Receptors Promises Improved Specificity

April 2009

Reports on NIDA researchers who developed a new tracer compound that binds readily to nicotine receptors and enhances positron emission tomography images.

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Brain Proteins Differ in Cocaine-Overdose Victims

December 2008

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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Henry Yamamura Obituary

December 2008

Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving

December 2008

Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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