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NIDA Notes Articles: Addiction Science

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Dr. Marilyn Huestis Q & A: Matching Drug Effects to Drug Concentrations

September 2013

Dr. Marilyn Huestis of NIDA’s Intramural Research Program talks about conducting research on drug effects with human subjects, developing tests to help law enforcement identify drugged drivers, and an assay to help identify children whose prenatal exposure to anti-HIV drugs may put them at risk for adverse developmental outcomes.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

October 2009

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Epigenetics: The Promise of a New Science

March 2008

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

October 2007
Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Extended Cocaine Exposure Impairs Cognitive Function in Rats

November 2009

Reports an animal study presenting evidence that cocaine causes cognitive deficits that can persist well into abstinence.

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French Government Honors Dr. Volkow

October 2010
Announces the 2009 International Prize, awarded by the French Institute of Health and Medical Research, to NIDA Director Dr. Nora D. Volkow.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Genetic Overlap Between Substance Abuse and Bipolar Disorder

April 2010
Describes a literature analysis reporting on the prevalence of people with bipolar disorder who also have a substance use disorder and discusses the genetic link that may contribute to this comorbidity.

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Henry Yamamura Obituary

December 2008

Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.

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How-To Guides Provide Tips for Publishing Addiction-Related Articles

April 2010
Describes a book and online tutorial for young investigators of addiction science that provides tips for publishing their studies in scholarly journals.

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