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NIDA Notes Articles: Addiction Science

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Studies Link Family of Genes to Nicotine Addiction

December 2009

Reports study results suggesting that genes for several acetylcholine receptor proteins influence early smoking responses and the likelihood of nicotine dependence.

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Stress-Induced Enzyme Compounds Methamphetamine Neurotoxicity

January 2014

Ketoprofen, an anti-inflammatory agent commonly prescribed to treat arthritis, reduces neuronal damage in rats that have been exposed to chronic stress and methamphetamine. If this finding of a recent NIDA-supported study extrapolates to humans, anti-inflammatory medications may gain a place in the treatment of methamphetamine addiction.

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Stimulus Money Will Fund a Surge in Knowledge

April 2009

Describes NIDA’s drug abuse and addiction research priorities for the use of the American Recovery and Reinvestment Act of 2009 funds.

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Stimulants in “Bath Salts” Produce Effects Similar to MDMA

August 2013

Mephedrone and methylone, two stimulants commonly found in designer drugs such as “bath salts,” act on the brain much like MDMA (Ecstasy).

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Stimulant Abusers' Regard for Future Improves With Memory Training

December 2011

Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

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Sensory Aspects of Smoking May Counter Bad Mood, Craving

October 2009

Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

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Scientists Pinpoint Brain's Sweet Tooth

April 2007
Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.

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Researchers Develop a New Tracer for Cannabinoid Receptor

March 2008
Describes a new chemical tracer that binds specifically to cannabinoid receptors making it potentially useful in future research to clarify the relationship between the receptors and drug abuse.

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Receptor Complexes Link Dopamine to Long-Term Neuronal Effects

October 2009

Reports on a discovery of previously unrecognized dopamine receptors in the brain that when triggered by drug abuse lead to potentially long-term neuronal effects.

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Reality Videos Bring NIDA Scientists to Web Site for Teens

April 2010
Highlights new video clips on NIDA's Web site for teens that explore the dangers of drug abuse and that address questions from youth and their parents on the topic.

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