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NIDA Notes Articles: Addiction Science

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Neuropeptide Promotes Drug-Seeking and Craving in Rats

October 2007
Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

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NIDA Will Contribute to Obesity Research

October 2007

Describes an NIH-wide obesity task force and research plan and explores some of the links between addiction and compulsive eating.

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NIDA's Newest Division Mines Clinical Applications From Basic Research

October 2007

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Tracing NET

October 2007
Describes research that has led to the development of a new tool, a new radiotracer, for studying the neurobiology of depression, attention deficit hyperactivity disorder, and stimulant abuse.

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NIDA Investigator Receives 2006 Waletzky Memorial Award

April 2007
Announces the recipient of a 2006 award for innovation in research on drug addiction and alcoholism, Dr. Yavin Shaham, and describes his research which focused on the stress-induced drug use relapse.

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Scientists Pinpoint Brain's Sweet Tooth

April 2007
Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.

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Nicotine Alters the Developing Rat Brain

February 2007
Describes animal studies that suggested exposure to the drug during gestation or adolescence may cause lasting alterations in reward and motivation circuits.

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Brain Changes Accompany Cocaine Withdrawal

February 2007
Summarizes an animal study of the neural changes in the amygdala portion of the brain that occur as a result of cocaine exposure followed by withdrawal of the drug.

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Cocaine Craving Activates Brain Reward Structures; Cocaine "High" Dampens Them

February 2007
Reports on a study that documenting changing emotional and neurobiological responses to cocaine with successive doses during a single session of drug taking.

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