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NIDA Notes Articles: Addiction Science

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Well-Known Mechanism Underlies Benzodiazepines' Addictive Properties

April 2012
New research establishes that benzodiazepines cause addiction in a way similar to that of opioids, cannabinoids, and the club drug GHB. The discovery opens the door to designing new benzodiazepines that counteract anxiety but are not addictive.

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New Method Uncovers How Internal States Influence the Living Brain to Change Behavior

March 2012
In an innovative NIDA-funded study, published in Cell, scientists introduced a modified dopamine receptor gene into the brain of a living vinegar fly

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In Animals, Receptor Puts Brakes on Nicotine Consumption

March 2012

New research suggests that differences in tobacco consumption reflect, in part, differences in the functional efficacy of a specific type of receptor in a pathway of the brain. In animal studies, nicotinic acetylcholine receptors with the α5 subunit played a key role in producing aversive responses to nicotine, thereby dissuading further consumption of the drug.

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Stimulant Abusers' Regard for Future Improves With Memory Training

December 2011

Researchers correlate stimulant abusers’ improved performance on a memory training exerc ise with reductions in delay discounting.

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Molecular Alterations of DNA Contribute to Persistence of Memory

November 2011
In a new series of studies tracing the molecular events that occur in the brain as memories are formed and preserved, researchers find that certain epigenetic changes may promote vulnerability to relapse.

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NIDA's Drug Abuse Research Advances Science as a Whole

November 2011

NIDA Director Dr. Nora D. Volkow summarizes instances where discoveries with broad implications for human health arose from scientists seeking answers to addiction problems.

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Office Meets Dynamic Challenges of Diversity

July 2011
Describes NIDA’s Special Populations Office which promotes addiction science that examines health disparities and foster research careers among members of underrepresented communities.

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Cocaine Alters Production of Hundreds of Proteins

March 2011

Describes research findings that show that chronic cocaine abuse may change the production of many proteins in the neurons of the brain’s reward system, aiding in our understanding how the drug causes addiction.

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Addiction Science Award Winners Announced

December 2010
Announces the 2010 high school student recipients of the Addiction Science Awards and describes their winning addiction-focused projects.

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Program Enhances Physician Knowledge on Substance Abuse

December 2010
Reports on an evaluation of the Chief Resident Immersion Training (CRIT) program to assess its effectiveness in improving knowledge, confidence, and preparedness to diagnose, manage, and teach about substance abuse.

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