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NIDA Notes Articles: People with Drug Use Disorders

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Study Supports Methadone Maintenance in Therapeutic Communities

December 2010

Describes a study that examined the effectiveness of combining two therapies for drug abuse addiction: methadone treatment and therapeutic communities, two approaches that are rarely combined.

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Brain Responds to Marijuana Cues in Familiar Manner

March 2011
Researchers found that the brain activity that takes place when cues trigger marijuana cravings is similar to the activity that accompanies cravings for other drugs.

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High Rates of Illegal Drug Use Among Alcohol-Dependent Adults

July 2011
Highlights data on the prevalence of rates of illegal drug use and nonmedical use of prescription drugs among adults dependant on alcohol, as compared with the general population.

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Methamphetamine Abuse Undermines Dental Health

July 2011
Describes research that sheds light on the correlation between increased dental disease and methamphetamine abuse.

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Intensive Interventions Reduce Risky Sexual Behaviors

July 2011
Discusses research that compares multiple sessions of motivational and behavioral training with that of a single intervention among male and female substance abusers to reduce high-risk sexual behaviors.

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NIDA Cosponsors Mentoring Service for Clinicians Advising Substance-Abusing Patients

July 2011

Highlights a free service that provides primary care clinicians with advice from experts in addiction medicine on addressing substance abuse with patients in the primary care setting.

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Computer-Based Intervention Offers Good Value for Money

July 2011

Reports on researchers who demonstrated the economic value of a computer-based treatment as an adjunct to standard addiction therapy.

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Treatment Dropout Linked With Elevated Stress Response

July 2011

Summarizes a study to determine whether a stress-related biological marker in saliva can predict how long a drug user will remain in treatment.

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Resting Brain Studies Shed New Light on Vulnerabilities

November 2011

Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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