Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.
Reports on research showing that the neurons that deliver dopamine to two regions of the brain's mesolimbic reward system respond differently to opioids, an important finding for drug treatment research.
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.
Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.
Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.
Summarizes research suggesting a physiological difference as the explanation for African-Americans' reported low tolerance for pain.