Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.
Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.
Reports on a series of animal experiments indicating that nicotine exposure during prenatal fetal development damages a set of receptors in the brain's auditory processing center.
Describes a study among people who had sustained brain injuries to investigate whether certain damaged areas of the brain are associated with the ability to quit smoking.
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.
Presents research findings linking 89 genes to drug abuse and dependence, found using genome-wide association studies, a new technique for identifying genes.