Describes research providing evidence that chronic methamphetamine abuse is associated with increased microglial cell activity in the brain leading to neurodegeneration.
Reports on research showing that newborns whose mothers abused methamphetamine during pregnancy showed lower rates of fetal growth as compared with unexposed newborns.
Highlights findings from a study of former methamphetamine abusers showing evidence of impairment in areas of the brain known to influence cognition, emotion, and decision making.
Highlights research showing methamphetamine abusers may have more difficulty than nonabusers in responding with empathy and self-control to people who are experiencing intense emotions.
New results extend previous findings that some methamphetamine-induced neuronal damage resolves after a year of abstinence.
Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.
In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.
Describes research results reporting that people who favor novelty have lower-than-average availability of a receptor that inhibits dopamine's release from neurons, which likely stimulates the activity of reward circuits.
Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.