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NIDA Notes Articles: Basic Science

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

October 2007

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Impacts of Drugs on Neurotransmission

October 2007

Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

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Stress Response May Underlie African- Americans' Reduced Pain Tolerance

October 2006

Summarizes research suggesting a physiological difference as the explanation for African-Americans' reported low tolerance for pain.

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High School Seniors Steadily Increase Nonmedical Use of Sedatives Over 15 years

October 2006

Highlights data from an annual national survey of youth showing a pattern of rising nonmedical use of sedatives among high school seniors.

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