Reports study results suggesting that genes for several acetylcholine receptor proteins influence early smoking responses and the likelihood of nicotine dependence.
Describes research providing evidence that chronic methamphetamine abuse is associated with increased microglial cell activity in the brain leading to neurodegeneration.
Reports an animal study presenting evidence that cocaine causes cognitive deficits that can persist well into abstinence.
Highlights findings from a study showing that nicotine triggers a surge in levels of the neurotransmitter dopamine in the brain's main reward area for cigarette smokers.
Reports on a discovery of previously unrecognized dopamine receptors in the brain that when triggered by drug abuse lead to potentially long-term neuronal effects.
Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.
Describes research exploring differences and similarities in the genetic profiles of African-Americans and European-Americans who are heavy smokers.
Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.
Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.
Highlights research showing methamphetamine abusers may have more difficulty than nonabusers in responding with empathy and self-control to people who are experiencing intense emotions.