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NIDA Notes Articles: Treatment

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Financial Strain Hinders Smoking Cessation

December 2011

Helping smokers deal with financial problems could improve their chances of staying abstinent after receiving treatment, according to a new study. Participants with the most financial strain had the least success in remaining abstinent.

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Antiretroviral Treatment Reduces Spread of HIV Among Injection Drug Users

April 2012
Expanded use of antiretroviral therapy in British Columbia reduced the spread of HIV among injection drug users and others in the province.

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Alleviation of Posttraumatic Stress Disorder May Improve Addiction Treatment

April 2012

Women with posttraumatic stress disorder (PTSD) who abused drugs responded better to substance abuse treatment after their PTSD symptoms improved, according to a recent study, which also found that reductions in substance abuse did not ease PTSD severity

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High Rates of Job Leaving Among Addiction Counselors

April 2012

Substance abuse counselors and clinical supervisors disclosed high job turnover rates in a survey of 27 treatment organizations.

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Buprenorphine During Pregnancy Reduces Neonate Distress

July 2012

Sublingual buprenorphine is a safe and effective alternative to methadone for treating opioid dependence during pregnancy, finds the Maternal Opioid Treatment: Human Experimental Research (MOTHER) study, a NIDA-supported clinical trial. Women who received either medication had similar pregnancy and birth outcomes, but infants born to women who received buprenorphine had milder symptoms of neonatal opioid withdrawal.

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More Convenient Preparations of Buprenorphine Pass Test

July 2012
Soluble-film preparations of buprenorphine suppressed heroin abusers’ withdrawal symptoms with no serious side effects in a recent clinical trial. They dissolved more rapidly in the mouth than the pill form of the medication, providing faster relief.

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Training Gaps for Evidence-Based Practices

July 2012

Ninety percent of privately funded substance abuse treatment programs in the United States offer cognitive behavioral therapy (CBT)...

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Intervention Boosts Treatment Participation, Abstinence Among Depressed Women

July 2012
Intensive case management was more effective in increasing treatment engagement and reducing alcohol consumption among depressed participants than among those who were not depressed, according to a followup analysis of a substance abuse treatment study involving women on welfare.

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Few Teens With Prescription Opioid Use Disorders Receive Treatment

July 2012

Fewer than 12 percent of adolescents who meet diagnostic criteria for prescription opioid abuse or dependence receive any treatment, according to an analysis of data from the 2005 to 2008 National Survey on Drug Use and Health. The most common reason the adolescents gave for not receiving treatment was their lack of perceived need for it.

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Potential Pain Medication Targets Peripheral Nerves

September 2012

Researchers report a significant advance in the search for medications that can suppress pain but avoid opioids’ abuse potential and other undesirable CNS effects. A new compound reduces mouse responses in animal models of neurogenic and chronic inflammatory (e.g., arthritic) pain. The compound, called UB937, enhances the natural pain-killing activity of the neurotransmitter anandamide, and exerts its analgesic effects entirely in peripheral tissues, without entering the brain.

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