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NIDA Notes Articles: Treatment
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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

October 2009

Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.
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Patch Delivers Buprenorphine for Heroin Detox

November 2009

Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.
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Antibody Fragment Removes Methamphetamine From the Brain

November 2009

Reports animal study findings on development of an antibody fragment that rapidly removes methamphetamine from the brain and discusses implications for treatment of overdose.
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Methadone Therapy in Prison Benefits Men a Year Out

November 2009

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.
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Computer-Based Interventions Promote Drug Abstinence

November 2009

Discusses the work of researchers who have begun to harness the potential of computers to reinforce and expand upon the well-established benefits of recovery therapy delivered by a counselor.
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Smokers Who Quit May Have Genetic Advantage

November 2009

Describes research providing evidence that genes may influence how successful a person is in quitting smoking and which cessation technique may work best for them.
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Naltrexone via Skin Patch Proves Effectiveness of New Technology

November 2009

Reports on a new device that creates tiny painless punctures in the skin to allow medication to flow evenly from a skin patch into dermal capillaries and the bloodstream.
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Recovery May Be Harder for Adolescents, Animal Study Suggests

December 2009

Reports animal study findings that suggest adolescents' heightened sensitivity to drug reward puts them at enhanced risk of addiction and may also increase their challenges in recovery.
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Anticipation of Methadone Enhances Brain Reactivity to Heroin Cues

December 2009

Describes findings of a study revealing that images of heroin preparation and injection can incite craving and excite brain areas associated with reward-seeking even in methadone-maintained patients.
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Test Substance Attenuates Signs of Cocaine Withdrawal in Rats

December 2009

Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

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