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NIDA Notes Articles: Stimulants

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Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

October 2006
Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.

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Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

August 2013

In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

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Marker for Neuronal Damage Resolves a Year after Methamphetamine

December 2011

New results extend previous findings that some methamphetamine-induced neuronal damage resolves after a year of abstinence.

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Medication Reduces Rats' Return to Methamphetamine Seeking

July 2011

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Methadone Reduces Rats' Cocaine Seeking

December 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Methadone Therapy in Prison Benefits Men a Year Out

November 2009

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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Methamphetamine Abuse Undermines Dental Health

July 2011
Describes research that sheds light on the correlation between increased dental disease and methamphetamine abuse.

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Mice With Genetic Alteration Eschew Cocaine

June 2008

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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Modafinil Normalizes Sleep During Early Cocaine Abstinence

December 2010
Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

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