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NIDA Notes Articles: Stimulants

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Marker for Neuronal Damage Resolves a Year after Methamphetamine

December 2011

New results extend previous findings that some methamphetamine-induced neuronal damage resolves after a year of abstinence.

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Male Rats’ Cocaine Exposure Affects Their Offspring’s Drug Responses

August 2013

In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.

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Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

October 2006
Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.

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Low Dopamine Receptor Availability May Promote Cocaine Addiction

April 2009

Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.

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Long-Term Cocaine Self-Administration Depresses Brain Activity

December 2008

Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Incentives Reduce Stimulant Abuse During Methadone Maintenance

April 2007

Summarizes a study on the use of incentives to encourage abstinence among methadone maintenance patients in outpatient programs.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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Fewer Young Adults Abuse Cocaine and Methamphetamine, National Survey Finds

December 2008

Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.

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Extended Cocaine Exposure Impairs Cognitive Function in Rats

November 2009

Reports an animal study presenting evidence that cocaine causes cognitive deficits that can persist well into abstinence.

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Drugs Contribute to High Rates of Sexually Transmitted Diseases Among Juvenile Offenders

July 2011

Describe a study of newly arrested youths where researchers found correlations between the youths' prevalence of these sexually transmitted diseases and their cocaine and marijuana use.

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