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NIDA Notes Articles: Stimulants

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012

Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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New Tools and Strategies to Bolster Behavioral Therapy

October 2010

Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

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Modafinil Normalizes Sleep During Early Cocaine Abstinence

December 2010
Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

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Mice With Genetic Alteration Eschew Cocaine

June 2008

Reports on a study involving researchers who successfully desensitized mice to cocaine by genetically altering their dopamine transporters.

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Methamphetamine Abuse Undermines Dental Health

July 2011
Describes research that sheds light on the correlation between increased dental disease and methamphetamine abuse.

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Methadone Therapy in Prison Benefits Men a Year Out

November 2009

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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Methadone Reduces Rats' Cocaine Seeking

December 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Medication Reduces Rats' Return to Methamphetamine Seeking

July 2011

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

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