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NIDA Notes Articles: Pain Medication

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Adolescent Cigarette, Alcohol Use Declines as Marijuana Use Rises

February 2013

Fewer teens are using cigarettes, alcohol, and most illicit drugs, according to NIDA’s latest Monitoring the Future study. Troubling  trends persist in marijuana use, however, and nonmedical prescription drug use remains a concern.

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Alcohol Abuse Makes Prescription Drug Abuse More Likely

March 2008

Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

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Basic Science Discoveries Yield Novel Approaches to Analgesia

September 2008

Describes research to develop new compounds that match or exceed the pain relief provided by opioids while avoiding their shortcomings.

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

October 2007

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults

October 2007

Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.

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Few Teens With Prescription Opioid Use Disorders Receive Treatment

July 2012

Fewer than 12 percent of adolescents who meet diagnostic criteria for prescription opioid abuse or dependence receive any treatment, according to an analysis of data from the 2005 to 2008 National Survey on Drug Use and Health. The most common reason the adolescents gave for not receiving treatment was their lack of perceived need for it.

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Meeting Reviews Progress On Prescription Opioid Misuse

April 2007
Describes a meeting of researchers and clinicians who gathered to discuss the challenges in balancing appropriate pain treatment with efforts to minimize prescription opioid misuse.

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Morphine Speeds AIDS Onset in Monkeys

June 2008

Highlights the work of investigators who discovered key ways in which morphine may accelerate the progression of AIDS in animal studies.

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Morphine-Induced Immunosuppression, From Brain to Spleen

June 2008

Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.

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Oxycodone Vaccine Passes Early Tests

May 2013

A new vaccine hindered the often-abused prescription opioids oxycodone and hydrocodone from entering the brain and suppressed one of the drugs’ signature central nervous system effects. The findings warrant continued development of the vaccine as a potential aid in the treatment of oxycodone and hydrocodone abuse and dependence.

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