NIDA Notes Articles: Opioids

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Oxycodone Vaccine Passes Early Tests

May 2013

A new vaccine hindered the often-abused prescription opioids oxycodone and hydrocodone from entering the brain and suppressed one of the drugs’ signature central nervous system effects. The findings warrant continued development of the vaccine as a potential aid in the treatment of oxycodone and hydrocodone abuse and dependence.

Patch Delivers Buprenorphine for Heroin Detox

November 2009

Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.

Prison Use of Medications for Opioid Addiction Remains Low

July 2011
Describes results from a nationwide survey among correctional facilities on the use of opioid replacement therapy for people who are addicted to heroin.

Reduced Longevity Among Male Heroin Abusers, 1962-1997

June 2008

Reviews the changing lifespan of heroin abusers as compared with that of the general U.S. population based on 1962-1997 data.

Reducing Postpartum Drug Use

December 2008

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

Scientists Pinpoint Brain's Sweet Tooth

April 2007
Reports on research that successfully traced rats’ liking for sweets to a 1-cubic millimeter site in the medial shell of the nucleus accumbens in the brain.

Some Teens Reporting Nonmedical Use of Prescriptions Develop Disorders

April 2010
Reports teen drug abuse based on 2006-2007 data from a national survey on drug use and health and compares differences by gender.

Study Finds Withdrawal No Easier With Ultrarapid Opiate Detox

October 2006
Presents findings from a clinical trial comparing ultrarapid, anesthesia-assisted detoxification with detoxification by traditional methods among patients addicted to heroin.

Study Supports Methadone Maintenance in Therapeutic Communities

December 2010
Describes a study that examined the effectiveness of combining two therapies for drug abuse addiction: methadone treatment and therapeutic communities, two approaches that are rarely combined.

Thoughts of Suicide May Persist Among Nonmedical Prescription Opiate Users

March 2013

People who use prescription opiates nonmedically are more likely to consider suicide than those who use these medications only appropriately or not at all. A recent NIDA-supported study also disclosed that the risk for suicidal thoughts remains elevated after cessation of use.

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Oxycodone Vaccine Passes Early Tests

Patch Delivers Buprenorphine for Heroin Detox

Prison Use of Medications for Opioid Addiction Remains Low

Reduced Longevity Among Male Heroin Abusers, 1962-1997

Reducing Postpartum Drug Use

Scientists Pinpoint Brain's Sweet Tooth

Some Teens Reporting Nonmedical Use of Prescriptions Develop Disorders

Study Finds Withdrawal No Easier With Ultrarapid Opiate Detox

Study Supports Methadone Maintenance in Therapeutic Communities

Thoughts of Suicide May Persist Among Nonmedical Prescription Opiate Users

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