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NIDA Notes Articles: Opioids

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Detoxification Services and Pharmacotherapies Lacking in Nation's Jails and Prisons

December 2010

Reports findings from a survey that revealed that although substance abuse is prevalent in jails and prisons, many correctional facilities do not offer detoxification services or therapies to aid in maintaining abstinence.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010

Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Some Teens Reporting Nonmedical Use of Prescriptions Develop Disorders

April 2010
Reports teen drug abuse based on 2006-2007 data from a national survey on drug use and health and compares differences by gender.

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Young Opioid Abusers Benefit From Extended Buprenorphine-Naloxone Treatment

April 2010
Reports on a study investigating the benefits of extended opioid maintenance therapy that included drug counseling and 12 weeks of therapy with buprenorphine and naloxone.

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Anticipation of Methadone Enhances Brain Reactivity to Heroin Cues

December 2009

Describes findings of a study revealing that images of heroin preparation and injection can incite craving and excite brain areas associated with reward-seeking even in methadone-maintained patients.

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Naltrexone via Skin Patch Proves Effectiveness of New Technology

November 2009

Reports on a new device that creates tiny painless punctures in the skin to allow medication to flow evenly from a skin patch into dermal capillaries and the bloodstream.

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Patch Delivers Buprenorphine for Heroin Detox

November 2009

Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.

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Methadone Therapy in Prison Benefits Men a Year Out

November 2009

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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Methadone Reduces Rats' Cocaine Seeking

December 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Reducing Postpartum Drug Use

December 2008

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

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