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NIDA Notes Articles: Tobacco

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Resting Brain Studies Shed New Light on Vulnerabilities

November 2011

Individuals with weak signaling in a nicotine-sensitive brain circuit were more vulnerable to nicotine dependence than those with stronger signaling, according to a study conducted while the subjects’ brains were in a resting state. A second resting-state study finds that the same circuit appears to mediate dependence associated with a genetic risk factor for smoking.

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Sensory Aspects of Smoking May Counter Bad Mood, Craving

October 2009

Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

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Smokers Who Quit May Have Genetic Advantage

November 2009

Describes research providing evidence that genes may influence how successful a person is in quitting smoking and which cessation technique may work best for them.

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Smoking and Drinking Continue to Decline, But Marijuana Stalls in Latest MTF Survey

October 2009

Highlights trends from a 2008 survey of teenage substance abuse, cigarette smoking and alcohol use and discusses the implications of these changing data.

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Standard Treatments Help Depressed Smokers Quit

April 2007
Describes a study comparing Staged Care Intervention, a combination treatment for smoking cessation, among smokers in outpatient treatment for depression and a control group.

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Stimulus Money Will Fund a Surge in Knowledge

April 2009

Describes NIDA’s drug abuse and addiction research priorities for the use of the American Recovery and Reinvestment Act of 2009 funds.

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Studies Link Family of Genes to Nicotine Addiction

December 2009

Reports study results suggesting that genes for several acetylcholine receptor proteins influence early smoking responses and the likelihood of nicotine dependence.

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Study Finds Genetic Influence on African Americans’ Smoking

November 2013

A meta-analysis of 13 genome-wide association studies of African Americans’ smoking patterns confirms the significance of genetic variation in region 15q25.1. The analysis also tentatively implicates several genome locations that have not previously been associated with smoking behaviors.

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Substance Abuse and Sexual Risk Show Town-Gown Divide

December 2009

Compares data on substance abuse and sexual risk among college students and their peers who do not attend college.

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Teen Substance Abuse Continues to Decline

March 2008

Reports on the prevalence of substance abuse among youth based on 2007 data from a national survey of behaviors, attitudes, and values.

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