Exposing rats to THC increases the likelihood that the animals will later self-administer nicotine. THC-exposed rats are also willing to work harder to obtain nicotine. When extrapolated to people, the findings suggest that THC’s pharmacological impact on the brain may make a person who uses marijuana more vulnerable to developing nicotine addiction, an underappreciated health consequence of marijuana use.
Driving under the influence of marijuana is a dangerous public health concern. NIDA researchers have discovered that breath expelled into a Breathalyzer-style collection device contained measurable amounts of THC for up to 2 hours after participants in a recent clinical trial smoked the drug.
Within the 2 weeks prior to responding to a nationwide survey, 28 percent of high school seniors were in a vehicle whose driver had been using marijuana or another illicit drug, or had drunk 5 or more alcoholic drinks.
Dr. Kevin M. Gray discusses why it’s the perfect time for discovering new evidence-based treatments for marijuana dependence. In an accompanying podcast, he discusses a clinical trial that examines NAC’s potential as a treatment for marijuana dependence among adults.