Reports prevalence rates of illicit drug abuse among youths and young adults based on 2007 data from a national survey of drug use and health.
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.
July 2011 Highlights data on the prevalence of rates of illegal drug use and nonmedical use of prescription drugs among adults dependant on alcohol, as compared with the general population.
February 2007 Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.
Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.
March 2008 Summarizes research on the effects of long-term regular cocaine abuse on the cardiovascular system in African Americans.
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.
Describes findings from an animal study showing that cocaine lowers availability of dopamine receptors in the basal ganglia, an area of the brain that includes portions of the reward system.
In a surprising finding, male rats who used cocaine sired male offspring who later exhibited blunted responses to the drug. Researchers determined the cause was an epigenetic alteration.
Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.