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NIDA Notes Articles: Cocaine

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How Drug Abuse Affects the Brain and Alters Behavior Are Key Questions Driving Division's Work

February 2007
Discusses the work of NIDA’s Division of Basic Neuroscience and Behavioral Research, the Institute’s locus for studies into the fundamental brain mechanisms underlying drug abuse and addiction.

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Behavioral Response to Novelty Foreshadows Neurological Response to Cocaine

February 2007
Describes evidence supporting the view that developmental differences in brain systems that use the neurotransmitter dopamine underlie age differences in susceptibility to drug abuse.

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Methylphenidate for Comorbid Cocaine Abuse, ADHD

October 2006
Describes an inpatient study investigating the effectiveness of sustained-release methylphenidate as a treatment for cocaine-addiction patients with ADHD.

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Brain Mechanism Turns Off Cocaine-Related Memory in Rats

October 2006
Describes a series of experiments that have added to evidence that a brain enzyme controls key memory processes that link drug experiences, the surroundings in which they take place, and the urge to repeat them.

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