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NIDA Notes Articles: Cocaine

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Drug Abuse at Highest Level in Nearly a Decade

December 2010

Reports on 2009 data indicating a rise in drug abuse in the United States and the factors that may have contributed to this increase.

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Cocaine Vaccine Helps Some Reduce Drug Abuse

December 2010

Reports on the results of a clinical trial that tested the effectiveness of a cocaine vaccine designed as a therapy for cocaine abuse and plans underway for a new study of 300 patients to confirm these results.

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Modafinil Normalizes Sleep During Early Cocaine Abstinence

December 2010
Describes a study investigating the effectiveness of modafinil in enhancing sleep among cocaine abusers who are currently abstinent.

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Deep Brain Stimulation Reduces Rats' Cocaine Seeking

December 2010
Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.

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Dr. Paul Kenny Receives the 2010 Waletzky Memorial Award

March 2011
Announces the recipient of a 2010 award for innovation in research on drug addiction and alcoholism and describes his work on increasing our understanding of the molecular foundation of addiction.

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Drugs Contribute to High Rates of Sexually Transmitted Diseases Among Juvenile Offenders

July 2011

Describe a study of newly arrested youths where researchers found correlations between the youths' prevalence of these sexually transmitted diseases and their cocaine and marijuana use.

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Neuropeptide Promotes Behaviors Tied to Addiction and Overeating

July 2011

Reports on several studies implicating a certain neuropeptide (a signaling molecule) in fostering addition and overeating and discusses implications for addiction treatment.

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High Rates of Illegal Drug Use Among Alcohol-Dependent Adults

July 2011
Highlights data on the prevalence of rates of illegal drug use and nonmedical use of prescription drugs among adults dependant on alcohol, as compared with the general population.

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Disruption of Neuron Production in Adult Rats Increases Cocaine Taking

November 2011
Drug abuse may diminish production of new neurons in the brain’s hippocampus and thereby increase vulnerability to drug addiction.

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New Class of Regulators for Addiction Genes

November 2011
New studies show that microRNAs, snippets of RNA implicated in a wide variety of biological processes, are involved in promoting and inhibiting cocaine addiction. The findings could pave a new path for the development of anti-addiction therapies.

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