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NIDA Notes Articles: Treatment Research
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Cocaine Locks Rats Into Unrewarding Behaviors

April 2009

Describes research with rats to better understand cocaine’s effect on the neural signaling in the learning circuits of the brain.
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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment

April 2009

Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.
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Stimulus Money Will Fund a Surge in Knowledge

April 2009

Describes NIDA’s drug abuse and addiction research priorities for the use of the American Recovery and Reinvestment Act of 2009 funds.
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Selenium Shows Promise as an Adjunct Therapy for HIV

December 2008

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.
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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008

Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.
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Lofexidine May Enhance Naltrexone Efficacy

December 2008

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.
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Methadone Reduces Rats' Cocaine Seeking

December 2008

Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.
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Henry Yamamura Obituary

December 2008

Remembers Henry I. "Hank" Yamamura, an eminent neuropharmacologist who pioneered radioligand binding assays, contributing valuable knowledge about neurotransmitter transporters and receptors.
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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women

December 2008

Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.
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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

December 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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