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NIDA Notes Articles: Treatment Research

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Journal Highlights Global Nexus of Drug Abuse and HIV/AIDS

October 2007
Reviews a journal supplement that compiles studies on drug-related HIV transmission, with a focus on injection drug use, in 16 different localities across the globe.

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Journal Highlights Opportunities in Hispanic Drug Abuse Research

February 2007
Reviews a journal supplement that compiles information on drug abuse research in the Hispanic population.

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Legal Pressure Increases Treatment Retention

April 2009

Presents data on the length of stay in substance abuse treatment among people who were in treatment as a result of legal pressure as compared with those in treatment voluntarily.

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Linking NIDA to Researchers on a Global Scale

June 2008

Highlights the NIDA International Program which works to strengthen international research networks, creating opportunities for global research collaboration, training, and scientific exchange.

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Lofexidine May Enhance Naltrexone Efficacy

December 2008

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Low-Cost Incentives Improve Outcomes in Stimulant Abuse Treatment

October 2006

Reports on a study investigating the use of incentives in the form of prizes to motivate outpatients to stay in behavioral therapy and remain drug free.

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Medical Care During Addiction Treatment Reduces Hospital Use

February 2007
Reports on an analysis comparing three types of addiction treatment programs: methadone maintenance programs, long-term residential programs, and nonmethadone programs.

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Medication Reduces Rats' Return to Methamphetamine Seeking

July 2011

Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010

Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Medications That Treat Opioid Addiction Do Not Impair Liver Health

December 2013

A trial of buprenorphine/naloxone (Bup/Nx) showed no evidence that the medicine was associated with liver damage. The drug gave results similar to those of methadone. The study data indicate that although most patients can be treated safely with either methadone or Bup/Nx without major concern for liver injury, clinicians are advised to continue to monitor the liver health of their patients who are on methadone or Bup/Nx therapy.


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