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NIDA Notes Articles: Treatment Research

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Serotonin System May Have Potential as a Target for Cocaine Medications

April 2007
Describes investigations to advance the development of potential drug abuse relapse prevention agents by targeting specific receptors of the neurochemical serotonin.

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Gene Experiment Confirms a Suspected Cocaine Action

October 2007

Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

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NIDA's Newest Division Mines Clinical Applications From Basic Research

October 2007

Describes the role of the Division of Clinical Neuroscience and Behavioral Research in NIDA’s drug abuse and addiction research plan.

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Journal Highlights Global Nexus of Drug Abuse and HIV/AIDS

October 2007
Reviews a journal supplement that compiles studies on drug-related HIV transmission, with a focus on injection drug use, in 16 different localities across the globe.

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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

October 2007

Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

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HIV Patients Show Better Immune Recovery With Early Initiation of HAART

March 2008
Presents evidence that among men and women with HIV, those who received early initiation of HAART therapy, those with higher CD4+ levels, achieved better immune recovery.

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Bupropion Reduces Meth's Subjective Effects and Cue-Induced Craving

March 2008

Describes a study investigating the use of the antidepressant bupropion as a potential therapy for methamphetamine addiction.

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Sertraline Does Not Help Methamphetamine Abusers Quit

March 2008

Describes a new research finding indicating that the antidepressant sertraline (Zoloft), prescribed to relieve depression during the methamphetamine withdrawal process, may make quitting harder.

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Combination Treatment Extends Marijuana Abstinence

March 2008
Describes research investigating the use of a treatment that combines vouchers and cognitive behavioral therapy as compared with the use of either treatment alone for marijuana abuse.

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Intervention Improves Employment Outlook For Methadone Patients

June 2008

Describes a study of unemployed methadone patients and the use of assertive outreach and motivational techniques to improve the patients’ employment outlook.

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