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NIDA Notes Articles: Relapse and Recovery

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Treatment Dropout Linked With Elevated Stress Response

July 2011

Summarizes a study to determine whether a stress-related biological marker in saliva can predict how long a drug user will remain in treatment.

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Neuropeptide Promotes Behaviors Tied to Addiction and Overeating

July 2011

Reports on several studies implicating a certain neuropeptide (a signaling molecule) in fostering addition and overeating and discusses implications for addiction treatment.

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Brain Responds to Marijuana Cues in Familiar Manner

March 2011
Researchers found that the brain activity that takes place when cues trigger marijuana cravings is similar to the activity that accompanies cravings for other drugs.

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Incentives Promote Abstinence

December 2010

Explores research findings on the value of motivational incentives to promote and reinforce abstinence from substances of abuse and encourage healthy behaviors.

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Program Enhances Physician Knowledge on Substance Abuse

December 2010
Reports on an evaluation of the Chief Resident Immersion Training (CRIT) program to assess its effectiveness in improving knowledge, confidence, and preparedness to diagnose, manage, and teach about substance abuse.

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Deep Brain Stimulation Reduces Rats' Cocaine Seeking

December 2010
Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.

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Intervention Improves Abstinence, Employment Among Welfare Recipients

December 2010
Reports research to study the effectiveness of an intensive case management program to aid female substance abusers who receive welfare in staying off drugs and finding employment.

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Study Supports Methadone Maintenance in Therapeutic Communities

December 2010

Describes a study that examined the effectiveness of combining two therapies for drug abuse addiction: methadone treatment and therapeutic communities, two approaches that are rarely combined.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

October 2010
Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

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