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NIDA Notes Articles: Relapse and Recovery

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Report Discusses Co-Occurrence of Drug Abuse and Other Mental Disorders

December 2009

Describes an updated report on the co-occurrence, or comorbidity, of substance use disorders and other psychiatric disorders such as ADHD, schizophrenia, and depression.

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Recovery Checkup System Helps Substance Abusers Who Have Mental Disorders

December 2009

Reports on a posttreatment intervention to support recovery that may be especially beneficial for substance abusers with co-occurring mental disorders.

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Recovery May Be Harder for Adolescents, Animal Study Suggests

December 2009

Reports animal study findings that suggest adolescents' heightened sensitivity to drug reward puts them at enhanced risk of addiction and may also increase their challenges in recovery.

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Anticipation of Methadone Enhances Brain Reactivity to Heroin Cues

December 2009

Describes findings of a study revealing that images of heroin preparation and injection can incite craving and excite brain areas associated with reward-seeking even in methadone-maintained patients.

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Test Substance Attenuates Signs of Cocaine Withdrawal in Rats

December 2009

Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

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Rare Glutamate Receptor Proliferates After Cocaine Withdrawal

December 2009

Reports findings that a rare neuroreceptor may be linked to the intensive cravings cocaine abusers experience during their first weeks of abstinence.

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Young Opioid Abusers Benefit From Extended Buprenorphine-Naloxone Treatment

April 2010
Reports on a study investigating the benefits of extended opioid maintenance therapy that included drug counseling and 12 weeks of therapy with buprenorphine and naloxone.

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New Tools and Strategies to Bolster Behavioral Therapy

October 2010

Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Brain Opioid Receptor Levels Predict Time to Cocaine Relapse

October 2010
Describes study findings revealing that cocaine abusers who maintain high levels of a certain receptor in their brain during early abstinence relapse sooner than abusers whose levels drop.

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