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NIDA Notes Articles: Medication Development

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NIDA Appoints New Director of the Intramural Research Program

December 2010
Announces NIDA’s new director of its intramural research program, Antonello Bonci, M.D., a leading researcher in neuropsychopharmacology.

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New Tools and Strategies to Bolster Behavioral Therapy

October 2010

Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

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Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

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Dr. Phil Skolnick Now Leads NIDA's Medications Development Efforts

April 2010
Announces the appointment of Dr. Phil Skolnick as NIDA’s director of the Division of Pharmacotherapies and Medical Consequences of Drug Abuse.

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Test Substance Attenuates Signs of Cocaine Withdrawal in Rats

December 2009

Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

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Naltrexone via Skin Patch Proves Effectiveness of New Technology

November 2009

Reports on a new device that creates tiny painless punctures in the skin to allow medication to flow evenly from a skin patch into dermal capillaries and the bloodstream.

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Combined Treatments Improve Dual Abstinence

October 2009

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Selenium Shows Promise as an Adjunct Therapy for HIV

December 2008

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.

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Lofexidine May Enhance Naltrexone Efficacy

December 2008

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

December 2008

Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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