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NIDA Notes Articles: 10/2009

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Suiting Treatment to the Nature of the Disease

October 2009

Highlights NIDA-sponsored research underway to understand and respond to substance abusers’ needs at all points of care, from the initial presentation for treatment through recovery.

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Receptor Complexes Link Dopamine to Long-Term Neuronal Effects

October 2009

Reports on a discovery of previously unrecognized dopamine receptors in the brain that when triggered by drug abuse lead to potentially long-term neuronal effects.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers

October 2009

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Manic Mice Show Heightened Sensitivity to Rewards

October 2009

Reports on an animal study suggesting that the manic stage of bipolar disorder promotes signs of drug abuse vulnerability by enhancing sensitivity to rewards, both natural and drug-related.

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Conferees Discuss Ways to Eliminate Disparities in Care

October 2009

Presents highlights of a meeting summit to discuss ways to eliminate disparities in care, particularly as they relate to drug abuse and HIV.

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Smoking and Drinking Continue to Decline, But Marijuana Stalls in Latest MTF Survey

October 2009

Highlights trends from a 2008 survey of teenage substance abuse, cigarette smoking and alcohol use and discusses the implications of these changing data.

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Ethnic Groups Have Contrasting Genetic Risks for Nicotine Addiction

October 2009

Describes research exploring differences and similarities in the genetic profiles of African-Americans and European-Americans who are heavy smokers.

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NIDA Reprises Online Chat Day

October 2009

Highlights NIDA’s second annual Chat Day where NIDA scientists and staff responded to drug abuse and addiction questions from teachers and students.

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Sensory Aspects of Smoking May Counter Bad Mood, Craving

October 2009

Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

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Abstinent Smokers' Nicotinic Receptors Take More Than a Month to Normalize

October 2009

Describes research revealing that for up to 6 weeks after smokers quit, their brain cells have more nicotine-binding receptors than nonsmokers, which may explain the struggle to quit.

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