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NIDA Notes Articles: 03/2008

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Alcohol Abuse Makes Prescription Drug Abuse More Likely

March 2008

Reports on results from a study showing that men and women with alcohol use disorders are more likely to report nonmedical use of prescription drugs than people who don't drink at all.

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Combination Treatment Extends Marijuana Abstinence

March 2008
Describes research investigating the use of a treatment that combines vouchers and cognitive behavioral therapy as compared with the use of either treatment alone for marijuana abuse.

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Bupropion Reduces Meth's Subjective Effects and Cue-Induced Craving

March 2008

Describes a study investigating the use of the antidepressant bupropion as a potential therapy for methamphetamine addiction.

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Chromosome 17 Harbors Opioid Dependence Genes

March 2008

Describes the work of researchers who have found a statistical link between one region on chromosome 17 and an increased risk of opioid dependence.

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HIV Patients Show Better Immune Recovery With Early Initiation of HAART

March 2008
Presents evidence that among men and women with HIV, those who received early initiation of HAART therapy, those with higher CD4+ levels, achieved better immune recovery.

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Sertraline Does Not Help Methamphetamine Abusers Quit

March 2008

Describes a new research finding indicating that the antidepressant sertraline (Zoloft), prescribed to relieve depression during the methamphetamine withdrawal process, may make quitting harder.

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Researchers Report on Progress of NIDA's Southern Africa Initiative

March 2008
Presents an update on NIDA’s Southern African Initiative, a program that aims to build research capacity and infrastructure in the area of addiction, particularly drug-related HIV transmission.

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Epigenetics: The Promise of a New Science

March 2008

Discusses the role of epigenetics, the study of cellular mechanisms that control gene expression and its impacts on health and behavior, in addiction research.

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Cocaine Can Mobilize Stored Dopamine

March 2008

Describes a study showing that cocaine, which increases dopamine levels, also can tap into an intracellular dopamine reserve pool.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

March 2008
Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

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