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NIDA Notes Articles: Research Briefs

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Peer Interaction Enhances Adolescent Rats' Drug Reward (April 2010)

Describes an animal study reporting that peer interaction enhances adolescent rats’ drug reward and discusses the impact of these findings to future research on drug reward in social context.

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Stroop Test Identifies Patients at Risk for Treatment Dropout (April 2010)

Reports on a study of cocaine abusers revealing that the Stroop test may predict which cocaine abusers are likely to drop out of therapy.

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Genetic Overlap Between Substance Abuse and Bipolar Disorder (April 2010)

Describes a literature analysis reporting on the prevalence of people with bipolar disorder who also have a substance use disorder and discusses the genetic link that may contribute to this comorbidity.

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Recovery May Be Harder for Adolescents, Animal Study Suggests (December 2009)

Reports animal study findings that suggest adolescents' heightened sensitivity to drug reward puts them at enhanced risk of addiction and may also increase their challenges in recovery.

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Anticipation of Methadone Enhances Brain Reactivity to Heroin Cues (December 2009)

Describes findings of a study revealing that images of heroin preparation and injection can incite craving and excite brain areas associated with reward-seeking even in methadone-maintained patients.

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Test Substance Attenuates Signs of Cocaine Withdrawal in Rats (December 2009)

Reports on several drugs that may ward off depression and anxiety, common withdrawal symptoms from cocaine, based on an animal study.

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Rats Reared Alone Show ADHD Signs (December 2009)

Describes an animal study showing that rats raised in isolation may prove useful in future studies exploring the neurobiology that links impulsivity and vulnerability to addiction.

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Methamphetamine Turns Helper Cells Into Destroyers (November 2009)

Describes research providing evidence that chronic methamphetamine abuse is associated with increased microglial cell activity in the brain leading to neurodegeneration.

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Patch Delivers Buprenorphine for Heroin Detox (November 2009)

Describes research on the effectiveness of a buprenorphine patch to alleviate opioid withdrawal symptoms of newly abstinent heroin abusers.

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Methadone Therapy in Prison Benefits Men a Year Out (November 2009)

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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