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NIDA Notes Articles: Research Briefs

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Methadone Therapy in Prison Benefits Men a Year Out (November 2009)

Describes clinical trial results providing evidence that methadone maintenance to men in prison can pay off in better retention in community treatment and reduced drug abuse following their release.

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Methamphetamine Abuse Alters Response to Facial Cues (October 2009)

Highlights research showing methamphetamine abusers may have more difficulty than nonabusers in responding with empathy and self-control to people who are experiencing intense emotions.

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Combined Treatments Improve Dual Abstinence (October 2009)

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers (October 2009)

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

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Sensory Aspects of Smoking May Counter Bad Mood, Craving (October 2009)

Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

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Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment (April 2009)

Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

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New Tracer for Nicotinic Receptors Promises Improved Specificity (April 2009)

Reports on NIDA researchers who developed a new tracer compound that binds readily to nicotine receptors and enhances positron emission tomography images.

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Adolescent Rats Self-Administer More Nicotine Than Adults (April 2009)

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

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Lofexidine May Enhance Naltrexone Efficacy (December 2008)

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Selenium Shows Promise as an Adjunct Therapy for HIV (December 2008)

Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.

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