NIDA Notes Articles: Research Briefs

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers (October 2009)

Describes research showing that cocaine abusers appear to have a rapid neural response to reward cues outside of their awareness, possibly signifying vulnerability to relapse.

Sensory Aspects of Smoking May Counter Bad Mood, Craving (October 2009)

Describes study findings revealing that the act of smoking, apart from actual or expected nicotine delivery, may soothe a smoker's negative mood.

Methamphetamine Abuse Alters Response to Facial Cues (October 2009)

Highlights research showing methamphetamine abusers may have more difficulty than nonabusers in responding with empathy and self-control to people who are experiencing intense emotions.

Combined Treatments Improve Dual Abstinence (October 2009)

Reports on a study investigating the effectiveness of a combined therapy of disulfiram and naltrexone for people who abuse cocaine and alcohol.

Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment (April 2009)

Reports on a study of men with co-occurring substance abuse and antisocial personality disorders and the potential benefit of judicially mandated addiction treatment.

New Tracer for Nicotinic Receptors Promises Improved Specificity (April 2009)

Reports on NIDA researchers who developed a new tracer compound that binds readily to nicotine receptors and enhances positron emission tomography images.

Adolescent Rats Self-Administer More Nicotine Than Adults (April 2009)

Highlights an animal study involving the self-administration of nicotine among adolescent and adult rats to gain understanding of their potential vulnerability to the substance.

Brain Proteins Differ in Cocaine-Overdose Victims (December 2008)

Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

Reducing Postpartum Drug Use (December 2008)

Highlights a computerized intervention that reduced new mothers' drug abuse in the first 4 months postpartum as reported in a clinical trial of 107 women who abused drugs.

Lofexidine May Enhance Naltrexone Efficacy (December 2008)

Highlights results from a pilot study suggesting that lofexidine, an anti-hypertensive medication, can enhance success rates among patients taking maintenance naltrexone to avoid opioid relapse.

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Drug Cues Outside Awareness Rapidly Trigger Brain's Emotion Centers (October 2009)

Sensory Aspects of Smoking May Counter Bad Mood, Craving (October 2009)

Methamphetamine Abuse Alters Response to Facial Cues (October 2009)

Combined Treatments Improve Dual Abstinence (October 2009)

Court Mandates Help Men With Antisocial Personality Disorders Stay in Treatment (April 2009)

New Tracer for Nicotinic Receptors Promises Improved Specificity (April 2009)

Adolescent Rats Self-Administer More Nicotine Than Adults (April 2009)

Brain Proteins Differ in Cocaine-Overdose Victims (December 2008)

Reducing Postpartum Drug Use (December 2008)

Lofexidine May Enhance Naltrexone Efficacy (December 2008)

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