NIDA Notes Articles: Featured Articles

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

March 2008
Reports on research of chronic cocaine abusers who may feel they are sleeping better during early abstinence revealed that the opposite may be true.

Study Links Anabolic Steroids to Brain Changes in Adolescent Female Mice

October 2007
Reports on an animal study finding that links anabolic steroids to brain changes in adolescent female mice, changes that can potentially lead to steroid abuse.

Gene Experiment Confirms a Suspected Cocaine Action

October 2007
Reports on the work of addiction researchers who are learning how acute and chronic cocaine exposure regulates certain genes, based on knowledge from developmental and cancer biology.

Impacts of Drugs on Neurotransmission

October 2007
Discusses the central importance of studying drugs' effects on neurotransmission and describes some of the most common experimental methods used in this research.

Neuropeptide Promotes Drug-Seeking and Craving in Rats

October 2007
Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.

Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

October 2007
Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.

Standard Treatments Help Depressed Smokers Quit

April 2007
Describes a study comparing Staged Care Intervention, a combination treatment for smoking cessation, among smokers in outpatient treatment for depression and a control group.

Depot Naltrexone Appears Safe and Effective for Heroin Addiction

April 2007
Presents results of a pilot study to investigate the safety and efficacy of a new long-lasting injectable formulation of naltrexone to treat of heroin addiction in an outpatient setting.

Uneven Regional Brain Development Contributes to Adolescent Risk-Taking

April 2007

Reports on the work of scientists who have linked impulsiveness and risk-taking among adolescents to immaturity of the brain region called the orbitofrontal cortex.

Interim Methadone Raises Odds of Enrolling in Comprehensive Treatment

April 2007
Reports on a study to investigate the use of methadone maintenance for heroin addicts wait-listed for a treatment program to encourage their likelihood to enroll in the program.

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Chronic Cocaine Abusers Have Occult Insomnia in Early Abstinence

Study Links Anabolic Steroids to Brain Changes in Adolescent Female Mice

Gene Experiment Confirms a Suspected Cocaine Action

Impacts of Drugs on Neurotransmission

Neuropeptide Promotes Drug-Seeking and Craving in Rats

Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats

Standard Treatments Help Depressed Smokers Quit

Depot Naltrexone Appears Safe and Effective for Heroin Addiction

Uneven Regional Brain Development Contributes to Adolescent Risk-Taking

Interim Methadone Raises Odds of Enrolling in Comprehensive Treatment

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Drugs, Brains, and Behavior - The Science of Addiction