NIDA Notes Articles: Featured Articles

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Brain Adaptation May Dampen Effects of Cocaine

October 2010
Reports evidence that a cocaine-induced change in the structure of brain cells represents an adaptive response that may limit the drug’s impact.

School-Wide Program Reduces Problem Behaviors and Improves Academic Outcomes

October 2010
Reports on a school-centered program for social and emotional development that was credited with reducing rates of substance abuse, violent behavior, and voluntary sexual activity among primary school children.

Crack Cocaine Promotes Progression of HIV Infection to AIDS

October 2010
Reports on two studies showing a high prevalence of HIV infection and more rapid progression to disability and death among drug abusers.

Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

October 2010
Reports on two studies that demonstrate the promise of treating addiction with medications that alleviate drug-induced alterations in signaling by the neurotransmitter glutamate.

Neuroimaging Challenges Common Assumption of Public Service Messaging

October 2010
Describes a study of smokers' brain function while they watched antismoking PSAs and findings suggesting that calmer ads may be more effective.

Behavior Game Played in Primary Grades Reduces Later Drug-Related Problems

April 2010
Presents research findings on a study to test the effectiveness of a classroom activity designed to instill appropriate behavior during children’s first 2 years of school.

Vouchers Boost Smoking Abstinence During Pregnancy

April 2010
Describes a voucher-based reinforcement therapy trial with pregnant smokers to determine its effectiveness in enhancing abstinence rates.

Young Opioid Abusers Benefit From Extended Buprenorphine-Naloxone Treatment

April 2010
Reports on a study investigating the benefits of extended opioid maintenance therapy that included drug counseling and 12 weeks of therapy with buprenorphine and naloxone.

Attention to Bipolar Disorder Strengthens Substance Abuse Treatment

April 2010
Describes a study of participants who had both substance abuse and bipolar disorder to investigate the potential benefits of integrated group therapy for this population.

Studies Link Family of Genes to Nicotine Addiction

December 2009
Reports study results suggesting that genes for several acetylcholine receptor proteins influence early smoking responses and the likelihood of nicotine dependence.

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Brain Adaptation May Dampen Effects of Cocaine

School-Wide Program Reduces Problem Behaviors and Improves Academic Outcomes

Crack Cocaine Promotes Progression of HIV Infection to AIDS

Medications That Normalize Brain Glutamate Reduce Drug-Seeking in Rats

Neuroimaging Challenges Common Assumption of Public Service Messaging

Behavior Game Played in Primary Grades Reduces Later Drug-Related Problems

Vouchers Boost Smoking Abstinence During Pregnancy

Young Opioid Abusers Benefit From Extended Buprenorphine-Naloxone Treatment

Attention to Bipolar Disorder Strengthens Substance Abuse Treatment

Studies Link Family of Genes to Nicotine Addiction

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Drugs, Brains, and Behavior - The Science of Addiction